Phenylephrine Simply because phenylephrine is definitely an adrenergic agent, it ought to be supplied with caution to patients with thyroid diseases, diabetic issues mellitus, and cardiovascular disease or These acquiring tricyclic antidepressants.
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Promethazine hydrochloride and phenylephrine hydrochloride syrup is indicated for that temporary relief of upper respiratory signs or symptoms, including nasal congestion, linked to allergy or perhaps the prevalent chilly.
They both comprise the exact same dose of Energetic substances promethazine hydrochloride/codeine phosphate six.25mg-10mg/5mL syrup.
Bone-Marrow Melancholy: Promethazine need to be utilized with caution in individuals with bone-marrow melancholy. Leukopenia and agranulocytosis happen to be claimed, generally when promethazine HCl continues to be Employed in Affiliation with other known marrow-harmful agents.
Promethazine: Promethazine is often a phenothiazine spinoff which differs structurally from the antipsychotic phenothiazines from the presence of the branched aspect chain and no ring substitution.
Akorn Prescription drugs has built a special formula that has important features and enhancements. The brand new taste is best, and it contains phenylephrine hydrochloride with promethazine hydrochloride. These attributes make their formulations special.
Lessen Seizure Threshold: Promethazine may possibly lower seizure threshold. It ought to be used with caution in folks with seizure Issues or in folks who are working with concomitant medications, for example narcotics or local anesthetics, which may also have an affect on seizure threshold.
Promethazine hydrochloride takes place as being a white to faint yellow, almost odorless, crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air.
What does Akorn syrup style like? Reliable Akorn syrup includes a thick, sweet taste with a delicate medicinal bitterness from codeine.
PAR and Hello-Tech are pharmaceutical makers. more info They equally manufacture promethazine with codeine syrup so the sole actual considerable big difference will be the taste and colour.
This merchandise has many variants. The choices could possibly be picked within the product or service site Item classes
Promethazine is metabolized through the liver to a variety of compounds; the sulfoxides of promethazine and N-demethylpromethazine are definitely the predominant metabolites showing in the urine.
Akorn thinks these new syrups are a crucial advancement. They supply successful and simple procedure selections for several conditions, including the widespread chilly and allergy symptoms.